BPC-157 vs KPV

A synthetic 15-amino-acid pentadecapeptide derived from a protein in human gastric juice, widely researched for its effects on soft tissue healing, tendon repair, and gut integrity.

A short three-amino-acid peptide derived from α-MSH. Potent anti-inflammatory, most used for gut inflammation, mast cell activation, and autoimmune flares.

BPC-157 appears to upregulate growth hormone receptor expression, promote angiogenesis through VEGF pathways, and accelerate collagen reorganisation in damaged tissue. Animal models show effects on ligament, tendon, muscle, bone, and gastric mucosa repair.

KPV inhibits NF-κB signalling and reduces pro-inflammatory cytokine production (TNF-α, IL-6). Unlike systemic immunosuppressants, it modulates inflammation without broad immunosuppression.

250–500 mcg per day (research protocols)

500 mcg – 1 mg daily (oral or subcutaneous)

~4 hours (parenteral)

Not well characterised

Subcutaneous, Intramuscular, Oral (stable form)

Oral, Subcutaneous

research-only

research-only

£16 · £3.2/mg via Peptides UK

£80 · £5.3/mg via My-Peptides