TB-500 vs GHK-Cu (injectable)

A synthetic fragment of the naturally occurring protein thymosin beta-4, used in research for its effects on cell migration, angiogenesis, and tissue repair following injury.

A naturally occurring copper tripeptide that activates over 4,000 genes involved in tissue remodelling and wound healing. Injectable form is used for systemic repair; topical form dominates cosmetics.

TB-500 binds to G-actin, regulating actin polymerisation and promoting cell migration to injured tissue. It upregulates VEGF-driven angiogenesis and modulates inflammatory cytokine profiles.

GHK-Cu binds copper ions and enters cells via copper-transport pathways. It modulates expression of genes governing collagen synthesis, angiogenesis, antioxidant defence, and skin-barrier repair.

2–10 mg per week (research protocols)

1–3 mg subcutaneous, 3–5x per week

~2–3 days

~1 hour (but downstream gene effects persist)

Subcutaneous, Intramuscular

Subcutaneous, Topical

research-only

research-only

£30 · £6.0/mg via Peptides UK

£80 · £1.6/mg via My-Peptides