Thymosin Alpha-1 vs KPV

A 28-amino-acid peptide originally isolated from the thymus gland. Approved in 30+ countries for hepatitis B/C and sepsis. Used off-label as a comprehensive immune modulator.

A short three-amino-acid peptide derived from α-MSH. Potent anti-inflammatory, most used for gut inflammation, mast cell activation, and autoimmune flares.

TA1 trains and optimises T-cell function, enhances NK cell activity, and modulates dendritic cell maturation. Sits at the junction of innate and adaptive immunity.

KPV inhibits NF-κB signalling and reduces pro-inflammatory cytokine production (TNF-α, IL-6). Unlike systemic immunosuppressants, it modulates inflammation without broad immunosuppression.

1.6 mg subcutaneous 2x per week

500 mcg – 1 mg daily (oral or subcutaneous)

~2 hours

Not well characterised

Subcutaneous

Oral, Subcutaneous

investigational

research-only

£30 · £6.0/mg via Peptides UK

£80 · £5.3/mg via My-Peptides