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Quick fact

Melanotan II half-life

How long Melanotan II stays active in the body, what that means for your dosing schedule, and where to buy.

Melanotan II half-life
~33 hours
Typical dose
100 mcg daily loading, 250–500 mcg maintenance

What half-life means for Melanotan II

Half-life is the time it takes for half the compound to be cleared from the body. Shorter half-lives (< 4h) usually require daily or multiple-daily dosing to maintain levels; longer half-lives (days) support once-weekly protocols.

For Melanotan II, the characterised half-life is ~33 hours. This directly informs the typical protocol of 100 mcg daily loading, 250–500 mcg maintenance.

Full mechanism, benefits, and dosing guidance on the main Melanotan II page.