NAD+ half-life
How long NAD+ stays active in the body, what that means for your dosing schedule, and where to buy.
NAD+ half-life
Short (hours); precursor loading is the long game
Typical dose
250–500 mg IV, or 100 mg subcutaneous, or 250–500 mg oral (as precursor)
What half-life means for NAD+
Half-life is the time it takes for half the compound to be cleared from the body. Shorter half-lives (< 4h) usually require daily or multiple-daily dosing to maintain levels; longer half-lives (days) support once-weekly protocols.
For NAD+, the characterised half-life is Short (hours); precursor loading is the long game. This directly informs the typical protocol of 250–500 mg IV, or 100 mg subcutaneous, or 250–500 mg oral (as precursor).
Full mechanism, benefits, and dosing guidance on the main NAD+ page.