Retatrutide half-life
How long Retatrutide stays active in the body, what that means for your dosing schedule, and where to buy.
Retatrutide half-life
~6 days
Typical dose
Phase 2 used 1–12 mg weekly; optimal dose pending Phase 3
What half-life means for Retatrutide
Half-life is the time it takes for half the compound to be cleared from the body. Shorter half-lives (< 4h) usually require daily or multiple-daily dosing to maintain levels; longer half-lives (days) support once-weekly protocols.
For Retatrutide, the characterised half-life is ~6 days. This directly informs the typical protocol of Phase 2 used 1–12 mg weekly; optimal dose pending Phase 3.
Full mechanism, benefits, and dosing guidance on the main Retatrutide page.