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Recovery & Injury Stack
The textbook peptide pairing for tendon, ligament, and muscle injury — combining angiogenesis and collagen reorganisation (BPC-157) with actin-driven cell migration (TB-500).
- Duration
- 8 weeks
- Experience
- intermediate
- Protocol
- 8 weeks
Peptides in this stack
BPC-157
A synthetic 15-amino-acid pentadecapeptide derived from a protein in human gastric juice, widely researched for its effects on soft tissue healing, tendon repair, and gut integrity.
TB-500
A synthetic fragment of the naturally occurring protein thymosin beta-4, used in research for its effects on cell migration, angiogenesis, and tissue repair following injury.
Rationale
BPC-157 and TB-500 work on complementary mechanisms. BPC-157 upregulates growth hormone receptor expression on tendon fibroblasts and drives VEGF-mediated angiogenesis. TB-500 binds G-actin and enables cell migration to sites of injury. Together, they create favourable conditions for rebuilding connective tissue.
Sample protocol
| Week | BPC-157 | TB-500 |
|---|---|---|
| 1–4 | 500 mcg daily SQ (split AM/PM) | 5 mg weekly SQ (split 2.5 mg × 2) |
| 5–8 | 250 mcg daily SQ | 2.5 mg weekly SQ |
Administer subcutaneously, ideally near the injury site for BPC-157. TB-500 is typically administered into the abdomen for systemic effect.
What this is for
- Chronic tendinopathy (patellar, Achilles, elbow)
- Partial muscle tears during rehabilitation
- Post-surgical recovery (soft tissue)
- Joint pain of inflammatory origin
What this is not for
- Acute fractures (use calcium/vitamin D and standard orthopaedic management)
- Autoimmune conditions (needs specialist input)
- Anyone in competition sport — both peptides are on the WADA prohibited list