Pinealon vs DSIP

A Russian-developed tripeptide (Glu-Asp-Arg) from pineal-gland research. Used for cognitive enhancement, stress regulation, and age-related decline.

A 9-amino-acid peptide first isolated in the 1970s that modulates delta-wave sleep and has analgesic and stress-reducing effects.

Pinealon modulates pineal and hypothalamic-pituitary axis signalling, with reported effects on dopamine, serotonin, and the HPA axis. Part of Khavinson's "bioregulator" class.

DSIP's mechanism remains incompletely characterised. It influences CRH/ACTH axis regulation, delta-wave sleep promotion, and pain-modulation pathways. Crosses the blood-brain barrier.

100–300 mcg daily (oral or injectable)

100–300 mcg subcutaneous at bedtime

Short — typically daily dosing

Short

Subcutaneous, Oral

Subcutaneous

research-only

research-only

Not yet listed

£15 · £3.0/mg via Peptides UK