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Quick fact

hCG half-life

How long hCG stays active in the body, what that means for your dosing schedule, and where to buy.

hCG half-life
~36 hours
Typical dose
250–500 IU 2–3x per week (TRT adjunct)

What half-life means for hCG

Half-life is the time it takes for half the compound to be cleared from the body. Shorter half-lives (< 4h) usually require daily or multiple-daily dosing to maintain levels; longer half-lives (days) support once-weekly protocols.

For hCG, the characterised half-life is ~36 hours. This directly informs the typical protocol of 250–500 IU 2–3x per week (TRT adjunct).

Full mechanism, benefits, and dosing guidance on the main hCG page.