The Michael Morelli Stack
Fitness coach Michael Morelli's self-disclosed peptide and bioregulator stack, spanning metabolic optimisation, sleep, cognition, and tissue repair.
Source post ↗Why this stack matters
Michael Morelli publicly documented this protocol on X as his "Current Peptide & BioRegulators" stack. It's a snapshot of what mid-2020s biohacking looks like at its most layered: not one peptide solving one problem, but a coordinated protocol spanning mitochondria, connective tissue, sleep, and skin.
The rationale behind each pairing
- 5-Amino-1MQ + SLU-PP-332 — two emerging small-molecule metabolic accelerants, targeting NNMT inhibition and ERR agonism respectively.
- BPC-157 + TB-500 — the textbook recovery pair.
- Epitalon + Pinealon + DSIP — pineal-peptide trio targeting circadian regulation, sleep architecture, and nocturnal restoration.
- GHK-Cu — systemic tissue remodelling and skin quality.
Buy the whole stack
Below you'll find the current cheapest in-stock offer for every peptide in the stack. Use the "Buy all" button to open each vendor in a new tab — we route through our affiliate tracker so your support funds the site.
The compounds in this stack
5-Amino-1MQ
A first-in-class NNMT (nicotinamide N-methyltransferase) inhibitor that redirects cellular energy toward metabolic acceleration. Early clinical pipeline; widely used in biohacker fat-loss protocols.
SLU-PP-332
An ERRα/β/γ pan-agonist that mimics the metabolic effects of exercise by activating oxidative-phosphorylation gene programs. Early-stage — animal data extraordinary, human data pending.
Epitalon
A tetrapeptide (Ala-Glu-Asp-Gly) developed in 1980s Soviet research, claimed to activate telomerase and modulate melatonin secretion from the pineal gland.
Pinealon
A Russian-developed tripeptide (Glu-Asp-Arg) from pineal-gland research. Used for cognitive enhancement, stress regulation, and age-related decline.
DSIP
A 9-amino-acid peptide first isolated in the 1970s that modulates delta-wave sleep and has analgesic and stress-reducing effects.
BPC-157
A synthetic 15-amino-acid pentadecapeptide derived from a protein in human gastric juice, widely researched for its effects on soft tissue healing, tendon repair, and gut integrity.
TB-500
A synthetic fragment of the naturally occurring protein thymosin beta-4, used in research for its effects on cell migration, angiogenesis, and tissue repair following injury.
GHK-Cu (injectable)
A naturally occurring copper tripeptide that activates over 4,000 genes involved in tissue remodelling and wound healing. Injectable form is used for systemic repair; topical form dominates cosmetics.